Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Drugs and diarrhea].

Manuel Haschke1

  • 1Departement Klinische Pharmakologie und Toxikologie, Universitätsspital Basel.

Therapeutische Umschau. Revue Therapeutique
|August 27, 2014
PubMed
Summary
This summary is machine-generated.

Drug-induced diarrhea is a common adverse event with various causes. Identifying the specific drug is key for managing this gastrointestinal issue, with treatments ranging from supportive care to specific medications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deprescribing of proton pump inhibitors in internal medicine in-patients: A retrospective observational study.

Exploratory research in clinical and social pharmacy·2026
Same author

Toxicity profile of supratherapeutic loperamide: a systematic review and dose-response analysis.

Clinical toxicology (Philadelphia, Pa.)·2026
Same author

Presentations Due to Priapism in an Urban Hospital in Switzerland.

Emergency medicine international·2026
Same author

Efficacy of paracetamol added to WHO step III opioids in chronic pain control: study protocol for a randomised, double-blind, placebo-controlled, non-inferiority, multicentre study in Switzerland.

BMJ open·2025
Same author

Intake of high-intensity statin after acute myocardial infarction assessed by direct drug concentration measurement: association with LDL-C response and coronary plaque modifications in the PACMAN-AMI trial.

European journal of preventive cardiology·2025
Same author

Monotherapy Blood Pressure Response and Control Rates in Treatment-Naïve Patients with Arterial Hypertension: A Randomized Comparison of Four Different Antihypertensive Drug Classes.

Kidney & blood pressure research·2025
Same journal

[Multimodal Cardiac Imaging: New Developments for Clinical Practice].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

State-of-the-Art Cardiac Imaging

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Clinical Medicine

Context:

  • Drug-induced diarrhea is a frequent adverse event.
  • Understanding its pathophysiology is crucial for patient care.
  • Identifying causative agents requires a thorough drug history.

Purpose:

  • To review the pathophysiological mechanisms of drug-induced diarrhea.
  • To emphasize the importance of a comprehensive drug history in diagnosis.
  • To outline treatment strategies for drug-induced diarrhea.

Summary:

  • Mechanisms include osmotic effects, altered fluid secretion/absorption, motility changes, and mucosal inflammation.
  • Many drug-induced diarrhea cases are mild and self-limiting.
  • Severe cases may require fluid/electrolyte replacement and symptomatic treatments like opioids or adsorbents.

Related Experiment Videos

Impact:

  • Improved diagnostic accuracy for drug-induced diarrhea.
  • Enhanced patient management through targeted therapeutic interventions.
  • Reduced morbidity associated with adverse drug reactions in the gastrointestinal tract.