[Freehand SPECT for navigation and sentinel node detection in breast cancer].

Area of Science:

• Oncology
• Surgical Innovation
• Medical Imaging

Background:

• Sentinel lymph node (SLN) biopsy is standard for staging N0 axillary breast cancer.
• Current SLN detection relies on isotopic and colorimetric methods.
• Limitations exist in preoperative identification accuracy.

Purpose of the Study:

• To evaluate the clinical utility of the Déclipse SPECT system for intraoperative SLN detection.
• To demonstrate the system's effectiveness in challenging cases where preoperative imaging is uninformative.

Main Methods:

• Utilized the Déclipse SPECT system, combining a gamma probe and infrared camera for 3D radioactive source detection.
• Employed the system for intraoperative SLN localization in a clinical case.
• Compared system performance against preoperative lymphoscintigraphy.

Main Results:

• The Déclipse SPECT system successfully detected and located the sentinel lymph node.
• The system proved valuable in a case where preoperative lymphoscintigraphy failed to provide informative identification.
• The mobile nature of the device facilitated intraoperative use.

Conclusions:

• The Déclipse SPECT system offers a promising tool for intraoperative sentinel lymph node detection in breast cancer surgery.
• Its 3D localization capability enhances surgical precision, particularly in complex cases.
• The system's mobility and integrated detection methods represent a significant advancement for SLN biopsy.