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Updated: Apr 25, 2026

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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Improved determination of G using two methods.

Terry Quinn1, Harold Parks1, Clive Speake2

  • 1BIPM, Pavillon de Breteuil, 92312 Sèvres cedex, France.

Physical Review Letters
|August 29, 2014
PubMed
Summary
This summary is machine-generated.

Researchers determined the Newtonian constant of gravitation (G) using a rebuilt apparatus. The new G value of 6.67545(18)×10⁻¹¹ m³kg⁻¹s⁻² confirms discrepancies with existing CODATA values.

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Area of Science:

  • Metrology
  • Fundamental Physics

Background:

  • Accurate determination of the Newtonian constant of gravitation (G) is crucial for fundamental physics.
  • Previous measurements of G have shown significant discrepancies, highlighting the need for refined experimental techniques.

Purpose of the Study:

  • To present a new, precise measurement of G using a completely rebuilt experimental apparatus at the BIPM.
  • To investigate the consistency of results obtained with updated experimental configurations.

Main Methods:

  • Utilized a torsion balance suspended from a Cu-Be strip, employing both free deflection (Cavendish) and electrostatic servo control modes.
  • Rebuilt the apparatus and conducted extensive tests on key parameters to ensure accuracy.

Main Results:

  • The new measurement yielded G = 6.67545(18)×10⁻¹¹ m³kg⁻¹s⁻² with a standard uncertainty of 27 ppm.
  • This result is statistically independent and consistent with the BIPM's 2001 measurement but differs from the CODATA 2010 value.
  • Confirmed a significant discrepancy between the BIPM results and the CODATA 2010 value for G.

Conclusions:

  • The new measurement contributes a precise value for G, reinforcing the observed divergence in reported values.
  • The statistical independence and consistency of the BIPM results offer a unique contribution to the ongoing determination of G.
  • Highlights the need for further investigation into the causes of discrepancies in G measurements.