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Updated: Apr 25, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
[Using mixture design to optimize preparation technology of gankeshuangqing dispersible tablets]
Objective:
To study the preparation process and the best prescription of Gankeshuangqing dispersible tablets.
Methods:
In order to select the prescription of Gankeshuangqing dispersible tablets and determine the dissolution, the disintegration time was used as index, single factor method and mixture design were used.
Results:
The compositions of Gankeshuangqing dispersible tablets prescription were 50% baicalin, 12.5% andrographolide, CaSO4 23.5%, micro-silica gel 4.1%, and L-HPC 11.3%. The disintegration time was (47 +/- 1) s. Dissolution tests showed that the dissolution rate of this product was higher than that of Gankeshuangqing capsules.
Conclusion:
The developed Gankeshuangqing dispersible tablets embodies the characteristics of dispersible tablets. The prescription is reasonable and the technology is feasible.
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