Emerging viral respiratory tract infections--environmental risk factors and transmission

Philippe Gautret1, Gregory C Gray2, Remi N Charrel3

  • 1Assistance Publique Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France; Aix Marseille Université, Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), Faculté de Médecine, Marseille, France.

Insights

Emerging respiratory viruses like MERS-CoV and H7N9 pose global health risks. Understanding their transmission and pathogenesis is crucial for effective prevention and control strategies.

Area of Science:

  • Virology
  • Public Health
  • Epidemiology

Background:

  • Recent emergence of novel respiratory viruses, including MERS-CoV, H7N9 influenza A, H3N2 variant influenza, and adenovirus 14p1.
  • MERS-CoV and H7N9 influenza A remain significant global public health threats.
  • Limited understanding of the pathogenesis and transmission modes for MERS-CoV and H7N9.

Purpose of the Study:

  • To highlight the urgent need for research into emerging viral respiratory pathogens.
  • To emphasize the gaps in knowledge regarding the epidemiology and transmission dynamics of these viruses.
  • To advocate for a coordinated global response to address these public health concerns.

Main Methods:

  • This study is a review and synthesis of current knowledge on emerging respiratory viruses.
  • Analysis of the public health impact and research gaps for MERS-CoV and H7N9.
  • Identification of the need for enhanced surveillance and research collaboration.

Main Results:

  • Several novel viruses causing respiratory infections have emerged globally in the last decade.
  • Key viruses of concern include Middle East respiratory syndrome coronavirus (MERS-CoV) and H7N9 influenza A.
  • Significant knowledge gaps exist in understanding the pathogenesis and transmission of these viruses.

Conclusions:

  • A coordinated global effort is essential to combat emerging viral respiratory infections.
  • Further research is critically needed to understand the epidemiology and transmission dynamics of MERS-CoV and H7N9.
  • Improved understanding will facilitate the development of effective intervention and prevention strategies against fatal respiratory diseases.

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