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Published on: August 22, 2018
Emerging viral respiratory tract infections--environmental risk factors and transmission
Philippe Gautret1, Gregory C Gray2, Remi N Charrel3
1Assistance Publique Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France; Aix Marseille Université, Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), Faculté de Médecine, Marseille, France.
Abstract:
The past decade has seen the emergence of several novel viruses that cause respiratory tract infections in human beings, including Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia, an H7N9 influenza A virus in eastern China, a swine-like influenza H3N2 variant virus in the USA, and a human adenovirus 14p1 also in the USA. MERS-CoV and H7N9 viruses are still a major worldwide public health concern. The pathogenesis and mode of transmission of MERS-CoV and H7N9 influenza A virus are poorly understood, making it more difficult to implement intervention and preventive measures. A united and coordinated global response is needed to tackle emerging viruses that can cause fatal respiratory tract infections and to fill major gaps in the understanding of the epidemiology and transmission dynamics of these viruses.
Insights
Emerging respiratory viruses like MERS-CoV and H7N9 pose global health risks. Understanding their transmission and pathogenesis is crucial for effective prevention and control strategies.
Area of Science:
- Virology
- Public Health
- Epidemiology
Background:
- Recent emergence of novel respiratory viruses, including MERS-CoV, H7N9 influenza A, H3N2 variant influenza, and adenovirus 14p1.
- MERS-CoV and H7N9 influenza A remain significant global public health threats.
- Limited understanding of the pathogenesis and transmission modes for MERS-CoV and H7N9.
Purpose of the Study:
- To highlight the urgent need for research into emerging viral respiratory pathogens.
- To emphasize the gaps in knowledge regarding the epidemiology and transmission dynamics of these viruses.
- To advocate for a coordinated global response to address these public health concerns.
Main Methods:
- This study is a review and synthesis of current knowledge on emerging respiratory viruses.
- Analysis of the public health impact and research gaps for MERS-CoV and H7N9.
- Identification of the need for enhanced surveillance and research collaboration.
Main Results:
- Several novel viruses causing respiratory infections have emerged globally in the last decade.
- Key viruses of concern include Middle East respiratory syndrome coronavirus (MERS-CoV) and H7N9 influenza A.
- Significant knowledge gaps exist in understanding the pathogenesis and transmission of these viruses.
Conclusions:
- A coordinated global effort is essential to combat emerging viral respiratory infections.
- Further research is critically needed to understand the epidemiology and transmission dynamics of MERS-CoV and H7N9.
- Improved understanding will facilitate the development of effective intervention and prevention strategies against fatal respiratory diseases.
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