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The use of bromodeoxyuridine-immunohistochemistry to identify transplanted fetal brain tissue
1Laboratory of Clinical Science, National Institute of Mental Health, National Institutes of Health Animal Center, Poolesville, MD 20837.
Journal of Neural Transplantation
|January 1, 1989
Abstract:
The immunohistochemical detection of the thymidine analog, 5-bromo-2'-deoxyuridine (BrdU) is shown to be a useful and reliable method to positively identify fetal brain transplants in standard histological preparations. This technique offers several advantages over the [3H]thymidine autoradiographic method, including being much more rapid and avoiding the use of radionuclides.