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Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
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[Argentine guidelines for urticaria and angioedema]
Jorge Máspero1, Hugo Cabrera2, Ledit Ardusso3
11Fundación CIDEA, Buenos Aires, 2 3 4 5 6 789, 1011Argentina.
Medicina
|September 10, 2014
Summary
Chronic urticaria (CU) management involves diagnosis and treatment updates. New guidelines recommend antihistamines as first-line, with omalizumab, cyclosporin A, or anti-leukotrienes for refractory cases.
Area of Science:
- Dermatology
- Allergy and Immunology
Context:
- Urticaria affects at least 20% of the population.
- Chronic urticaria (CU) presents as spontaneous (SCU) or induced (ICU).
- Diagnosis is primarily clinical, with provocation tests for ICU.
Purpose:
- To summarize current news in chronic urticaria diagnosis and treatment.
- To provide evidence-based management suggestions.
- To update on recent therapeutic advancements.
Summary:
- First-line treatment for CU involves second-generation antihistamines.
- Increased doses of H1 antihistamines are used as a second-line approach.
- Omalizumab, cyclosporin A, and anti-leukotrienes are recommended third-line options for refractory CU.
Impact:
- Improves quality of life for chronic urticaria patients.
- Reduces reliance on systemic steroids for difficult-to-treat cases.
- Offers updated, evidence-based strategies for clinicians managing chronic urticaria.
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