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Updated: Apr 23, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
A non-invasive NMR relaxometric characterization of the cyclododecane-solvent system inside porous substrates
F Presciutti1, B Doherty, C Anselmi
1Dipartimento di Chimica, Università degli Studi di Perugia, Perugia, Italy; Centro di eccellenza SMAArt (Scientific Methodologies applied to Archaeology and Art) c/o Dipartimento di Chimica, Università degli Studi di Perugia, Perugia, Italy.
Abstract:
With the aim of deepening the knowledge on the behavior of cyclododecane (CDD) as a temporary consolidant agent for weathered stones, NMR longitudinal and transverse relaxation decays have been exploited to follow the distribution of cyclododecane solutions into porous matrices. By measuring as function of time the relaxation decay constants of CDD solutions dropped onto porous supports, it has been possible to differentiate the step encompassing the solvent evaporation, which determines the consolidant migration within the matrix, from that governing the consolidant sublimation, which is related to the consolidation effectiveness over time.
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