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Self-powered Imbibing Microfluidic Pump by Liquid Encapsulation: SIMPLE.

Tadej Kokalj1, Younggeun Park, Matjaž Vencelj

  • 1IMT, Ljubljana, Slovenia. tadej.kokalj@imt.si.

Lab on a Chip
|September 19, 2014
PubMed
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A novel Self-powered Imbibing Microfluidic Pump by Liquid Encapsulation (SIMPLE) offers a disposable, cost-effective solution for point-of-care diagnostics. This autonomous pump requires no external power, enabling rapid, on-demand sample processing.

Area of Science:

  • Microfluidics
  • Biomedical Engineering
  • Materials Science

Background:

  • Point-of-care (POC) diagnostics require reliable, self-powered microfluidic pumps for rapid analysis.
  • Existing microfluidic pumps often need external power sources, limiting their application in resource-constrained settings.

Purpose of the Study:

  • To develop and characterize a novel, disposable, and autonomous microfluidic pump for POC applications.
  • To demonstrate a cost-effective fabrication method for the proposed microfluidic pump.

Main Methods:

  • A Self-powered Imbibing Microfluidic Pump by Liquid Encapsulation (SIMPLE) was designed using paper as a porous material for liquid suction.
  • The pump's operation relies on capillary action to create reduced pressure for sample flow in microfluidic channels.

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  • Flow rates were programmed by altering the shape of the porous material, and fabrication utilized a foil-laminating technique.

    • Main Results:

    • The SIMPLE pump demonstrated autonomous operation, activated by a simple fingertip press.
    • Programmable flow rates (0.07–0.17 μL s⁻¹) were achieved by varying paper geometry.
    • The pump successfully processed 17 μL of sample, with potential for higher volumes, using a cost-efficient fabrication method.

    Conclusions:

    • The SIMPLE pump provides a robust, cost-effective, and autonomous solution for self-powered microfluidic POC devices.
    • This innovation facilitates the development of disposable diagnostic chips for large-scale manufacturing.
    • The technology addresses the critical demand for accessible and efficient POC diagnostic tools.