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Histological changes in vocal fold growth and aging.
1Department of Otolaryngology - Head and Neck Surgery, University of California, Davis, Sacramento, California, USA.
Current Opinion in Otolaryngology & Head and Neck Surgery
|September 19, 2014
Summary
Vocal fold histology changes throughout life, impacting voice production. New research enhances our understanding of these changes, leading to better voice disorder therapies.
Area of Science:
- Laryngology
- Voice Science
- Histology
Background:
- Vocal fold microarchitecture descriptions exist but lifespan evolution is debated.
- Aging population and pediatric voice disorders necessitate understanding vocal fold changes.
Purpose of the Study:
- To review contemporary understanding of evolving vocal fold histology.
- To discuss implications for voice production throughout the lifespan.
Main Methods:
- Utilizing novel biotechnology applications.
- Developing and employing animal models.
- Analyzing human specimens.
Main Results:
- Gained insights into histologic vocal fold changes across the lifespan.
- Observed changes in both health and disease states.
Conclusions:
- Advanced knowledge supports comprehensive vocal fold histology models.
- Led to development of innovative therapies for voice disorders.
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