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Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis
Published on: December 8, 2023
Chemical constituents from the stems of Excoecaria acertiflia
Sheng-Zhuo Huang1, Huai-Rong Luo, Qing-Yun Ma
1Hainan Key Laboratory for Research and Development of Natural Product from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P. R. China, (phone/fax: +86-898-66989095).
Abstract:
Six new compounds, including two diterpenoids excocarinols F and G (1 and 2, resp.), two carotane (daucane) sesquiterpenoids excoecafolinols A and B (3 and 4, resp.), one lignanoid compound, excoecanol A (5), and one simple phenol, excoecanol B (6), together with 17 known compounds, were isolated from the BuOH extract of Excoecaria acerifolia Didr. stems. Their structures were elucidated through the analysis of the spectroscopic data. The AChE-inhibitory activities of 17 compounds were evaluated and revealed that four of them possessed moderate inhibitory activities against AChE.
