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Published on: August 8, 2025
Infantile and congenital hemangiomas
Marilyn G Liang1, Ilona J Frieden2
1Dermatology Program, Boston Children׳s Hospital, 300 Longwood Ave, Boston, Massachusetts 02115.
Infantile hemangiomas (IHs), common in infants, often resolve naturally. Treatment is reserved for IHs causing ulceration, disfigurement, or functional impairment, with congenital hemangiomas (CHs) being a distinct entity.
Area of Science:
- Pediatric Vascular Anomalies
- Dermatology
- Neonatal Medicine
Background:
- Infantile hemangiomas (IHs) are the most frequent benign vascular tumors in infants.
- Most IHs involute spontaneously, often without lasting effects, negating the need for treatment.
- Intervention is indicated for specific complications such as ulceration, cosmetic concerns, or functional impairment.
Purpose of the Study:
- To differentiate infantile hemangiomas (IHs) from congenital hemangiomas (CHs).
- To outline the natural history and risk factors associated with IHs.
- To discuss the management strategies for IHs and CHs.
Main Methods:
- Review of clinical findings and natural history of infantile hemangiomas.
- Histological and immunohistochemical comparison of IHs and congenital hemangiomas.
- Analysis of indications for treatment and management approaches for both entities.
Main Results:
- Infantile hemangiomas typically involute without intervention.
- Treatment is reserved for IHs with ulceration, disfigurement, or functional impairment.
- Congenital hemangiomas are distinct from IHs, with unique histological and clinical characteristics.
Conclusions:
- Understanding the natural history of IHs is crucial for appropriate management decisions.
- Congenital hemangiomas represent a separate clinical entity requiring distinct consideration.
- Management should be individualized based on IH characteristics, potential complications, and patient factors.
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