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[Pain relief by high-dose medroxyprogesterone acetate in advanced prostatic cancer]
I Sasagawa1, S Satomi, K Umeda
1Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University.
Hinyokika Kiyo. Acta Urologica Japonica
|April 1, 1989
Abstract:
The effect of high-dose medroxyprogesterone acetate was studied in 7 patients with advanced prostatic cancer. Results in 7 patients were no change (NC) in 5 (71%) and progressive disease (PD) in 2 patients (29%). However, pain relief was obtained in 6 of the 7 patients (86%). As side effects, 2 patients (29%) showed moon-face and 2 patients weight gain (29%). These results indicate that treatment of high-dose medroxyprogesterone acetate is useful for pain relief in patients with advanced prostatic cancer.