Related Experiment Video
Updated: Apr 23, 2026
08:34
A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
Published on: October 16, 2015
9.5K
Protein-based fluorescent metal nanoclusters for small molecular drug screening
Yong Yu1, Siu Yee New, Jianping Xie
1Institute of Materials Research and Engineering, 3 Research Link, Singapore 117602. tanyn@imre.a-star.edu.sg xd-su@imre.a-star.edu.sg.
Chemical Communications (Cambridge, England)
|September 26, 2014
Abstract:
A facile drug screening method based on synthesis of fluorescent gold nanoclusters inside albumin proteins loaded with small molecular drugs and comparing the relative fluorescence intensities of the resultant gold nanoclusters has been developed and successfully applied for the quantitative measurement of drug-protein binding constants.
