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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Role of Vitamins in Maintaining Bone Health01:25

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Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
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Concern and risk perception: effects on osteoprotective behaviour.

A L Barcenilla-Wong1, J S Chen1, L M March1

  • 1Institute of Bone and Joint Research, Kolling Institute of Medical Research, University of Sydney, Sydney, NSW 2065, Australia.

Journal of Osteoporosis
|October 3, 2014
PubMed
Summary

Women's concern about osteoporosis and fracture risk influences medical advice and bone density testing. However, perceived risk doesn't always translate to osteoporosis treatment, highlighting an educational gap.

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Area of Science:

  • Gerontology
  • Public Health
  • Epidemiology

Background:

  • Osteoporosis poses a significant health risk, particularly for women.
  • Understanding factors influencing bone health behaviors is crucial for prevention and management.

Purpose of the Study:

  • To investigate the impact of concern and perceived risk of osteoporosis and fracture on health-seeking behaviors.
  • To examine the association between concern and risk perception and the use of calcium/vitamin D supplementation, medical advice, bone mineral density (BMD) testing, and antiosteoporosis medication (AOM).

Main Methods:

  • Analysis of data from 1,095 untreated female Australian participants in the Global Longitudinal study of Osteoporosis in Women (GLOW).
  • Self-administered questionnaires assessed calcium and vitamin D supplementation, seeking medical advice, BMD testing, and AOM use.
  • Logistic regression was employed to analyze the relationships between concern, perceived risk, and health behaviors.

Main Results:

  • Increased concern significantly raised the likelihood of seeking medical advice but did not impact screening or treatment.
  • Heightened self-perceived risks of osteoporosis and fracture increased the likelihood of seeking medical advice and BMD testing.
  • Elevated self-perceived fracture risk was associated with increased AOM use, while supplementation use showed no significant association with concern or risk perception.

Conclusions:

  • Concern and risk perceptions are linked to specific bone-protective actions like seeking medical advice and BMD testing.
  • A notable gap exists between perceived osteoporosis risk and the uptake of AOM, indicating a need for improved educational strategies.
  • Future health education programs should emphasize the direct link between osteoporosis and fracture risk to encourage appropriate treatment adherence.