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Related Experiment Video

Updated: Apr 23, 2026

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

Published on: November 11, 2025

Dry eye: an inflammatory ocular disease.

Michelle Hessen¹, Esen Karamursel Akpek¹

¹Ocular Surface Diseases & Dry Eye Clinic, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Journal of Ophthalmic & Vision Research

|October 4, 2014

Summary

Keratoconjunctivitis sicca (dry eye) involves tear film abnormalities and ocular surface inflammation. Novel treatments targeting inflammation, such as cyclosporine A and corticosteroids, offer effective management and clinical improvement for dry eye disease.

Keywords:

Dry Eye Inflammation Keratoconjunctivitis Sicca Sjӧgren’s Syndrome Treatment

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In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation

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Published on: November 11, 2025

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

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Establishment of A Mouse Model of Aqueous Deficiency Dry Eye

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Published on: November 1, 2024

Area of Science:

Ophthalmology
Immunology

Background:

Keratoconjunctivitis sicca (dry eye) is a prevalent ocular condition affecting millions.
It is characterized by pre-corneal tear film abnormalities and ocular surface inflammation.

Purpose of the Study:

To review novel treatments for dry eye disease.
To highlight the role of inflammation in dry eye pathogenesis.

Main Methods:

Review of current literature on dry eye treatments.
Analysis of anti-inflammatory therapeutic strategies.

Main Results:

Inflammation is a key factor in dry eye disease.
Several medications, including cyclosporine A, corticosteroids, and autologous serum, demonstrate efficacy.
These treatments lead to significant clinical improvements in dry eye patients.

Conclusions:

Targeting inflammatory pathways is crucial for managing dry eye.
Current anti-inflammatory medications provide effective relief for dry eye symptoms and signs.