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Updated: Apr 23, 2026
Glass-Based Devices to Generate Drops and Emulsions
Published on: April 5, 2022
Wafer-scale fabrication of glass-FEP-glass microfluidic devices for lipid bilayer experiments
Johan G Bomer1, Alexander V Prokofyev, Albert van den Berg
1BIOS - Lab on a Chip group, MESA+ Institute for Nanotechnology, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands. s.legac@utwente.nl.
Abstract:
We report a wafer-scale fabrication process for the production of glass-FEP-glass microdevices using UV-curable adhesive (NOA81) as gluing material, which is applied using a novel "spin & roll" approach. Devices are characterized for the uniformity of the gluing layer, presence of glue in the microchannels, and alignment precision. Experiments on lipid bilayers with electrophysiological recordings using a model pore-forming polypeptide are demonstrated.
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