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Updated: Apr 22, 2026

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity
Published on: November 8, 2016
Is autoimmunity a side-effect of interleukin 2 production?
G Krämer1, K Schauenstein, G Wick
1Institute for General and Experimental Pathology, University of Innsbruck, Medical School, A- 6020 Innsbruck, Austria.
Abstract:
Because it has a role in lymphocyte activation, interleukin 2 (IL-2) has been tried as a therapeutic agent in several types of immune dysfunction in animals and man. Here, Georg Wick and his colleagues discuss the possibility that IL-2 production initiates and perpetuates autoimmune disease, and express caution about the clinical use of IL-2.
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