The role of the T3 molecular complex in antigen recognition and subsequent activation events
C D Tsoukas1, M Valentine, M Lotz
1Department of Basic and Clinical Research, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, La Jolla, California 92037, USA.
Abstract:
Monoclonal antibodies raised against human T lymphocytes have identified several cell surface structures that are intimately involved in T-cell function. Perhaps the most familiar is the structure labelled T3. First identified as an antigen five years ago, it is now known to be a complex of at least three molecular species that is found on all T lymphocytes. There seems little doubt that T3 is closely associated with the antigen receptor on these cells, but how? A new (and different) answer is proposed in each of the following articles.
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