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Serial MR Imaging in Suprasellar Xanthogranuloma: Growth Pattern and New Lesions
Balaguruswamy Madan Mohan1, Ezaz Mohamed1, Sunil Kumar Jain1
1Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Abstract:
Xanthogranuloma is a rare lesion of the sellar-suprasellar region. We describe a case of suprasellar xanthogranuloma in whom serial MRI revealed features that have not been previously described--development of dural tail, vascular encasement and intra-axial lesions in posterior fossa.
Insights
We report a rare case of sellar-suprasellar xanthogranuloma. Serial MRI revealed novel findings including dural tail, vascular encasement, and posterior fossa intra-axial lesions.
Area of Science:
- Neuropathology
- Neuroradiology
- Neuro-oncology
Background:
- Xanthogranuloma is an uncommon inflammatory lesion.
- Sellar-suprasellar region involvement is rare.
Observation:
- A case of suprasellar xanthogranuloma is presented.
- Serial magnetic resonance imaging (MRI) was performed.
Findings:
- The lesion demonstrated a developing dural tail sign.
- Vascular encasement by the xanthogranuloma was observed.
- New intra-axial lesions appeared in the posterior fossa.
Implications:
- These findings expand the known imaging spectrum of xanthogranuloma.
- Understanding these features aids in differential diagnosis of sellar-suprasellar masses.
- Further research may elucidate the pathogenesis of these imaging characteristics.

