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Updated: Apr 22, 2026

Orthotopic Hind Limb Transplantation in the Mouse
Published on: February 12, 2016
Transplant in the 21st century
Kim Zuber1, Tricia Howard, Jane Davis
1Kim Zuber practices at Metropolitan Nephrology in Alexandria, Va., and is AAPA Outstanding PA of the Year. Tricia Howard is director of preclinical education at South University in Savannah, Ga., and chair of the National Kidney Foundation's council of advanced practitioners. Jane Davis is a nurse practitioner at the University of Alabama at Birmingham and a member of the National Kidney Foundation's board of directors and the American Society of Nephrology's CME committee. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Organ transplantation saves lives through advanced techniques and better management. Current donor and recipient criteria are reviewed, with efforts to expand the donor pool.
Area of Science:
- Medical Science
- Surgical Innovation
- Immunology
Background:
- Organ transplantation has significantly improved patient survival for end-stage organ failure.
- Advances in surgical techniques and immunosuppressive therapy have been key to progress.
- The scope of transplantable organs has expanded considerably over time.
Observation:
- Donor and recipient eligibility criteria differ based on the specific organ.
- Historical evolution of transplant practices has led to current standards.
- There is an ongoing need to increase the availability of donor organs.
Findings:
- Modern organ transplantation utilizes refined surgical methods and pharmacological interventions.
- Established criteria guide donor selection and recipient suitability.
- New strategies are being developed to enhance organ donor recruitment.
Implications:
- Continued advancements in transplantation offer hope for more patients with organ failure.
- Understanding donor-recipient dynamics is crucial for successful transplant outcomes.
- Expanding the donor pool is vital for meeting the growing demand for organ transplants.
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