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Quantitative assessment of synovitis in Legg-Calvé-Perthes disease using gadolinium-enhanced MRI
David C Neal1, Jack C O'Brien, Jamie Burgess
1aCenter of Excellence in Hip Disorders, Texas Scottish Rite Hospital for Children bUniversity of Texas Southwestern Medical Center, Dallas, Texas, USA.
Abstract:
A quantitative method to assess hip synovitis in Legg-Calvé-Perthes disease (LCPD) is not currently available. To develop this method, the areas of synovial enhancement on gadolinium-enhanced MRI (Gd-MRI) were measured by two independent observers. The volume of synovial enhancement was significantly increased in the initial and the fragmentation stages of LCPD (Waldenström stages I and II), with a persistence of synovitis into the reossification stage (stage III). The Gd-MRI method had high interobserver and intraobserver agreements and may serve as a useful method to monitor the effect of various treatments on hip synovitis in LCPD.
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