Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[8;21 translocation and leukemia].

M Rochon, L Vaillancourt, J Lépine

    L'Union Medicale Du Canada
    |November 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Identifying potential predictors of the risk of surgical site infection following cardiac surgery: a scoping review.

    The Journal of hospital infection·2024
    Same author

    A comprehensive qualitative investigation of the factors that affect surgical site infection prevention in cardiac surgery in England using observations and interviews.

    The Journal of hospital infection·2024
    Same author

    Sex differences in surgical site infections following coronary artery bypass grafting: a retrospective observational study.

    The Journal of hospital infection·2024
    Same author

    Third-trimester development of left-sided abdominal wall defect.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
    Same author

    Barriers and facilitators for surgical site infection surveillance for adult cardiac surgery in a high-income setting: an in-depth exploration.

    The Journal of hospital infection·2023
    Same author

    Image-based digital post-discharge surveillance in England: measuring patient enrolment, engagement, clinician response times, surgical site infection, and carbon footprint.

    The Journal of hospital infection·2023

    This study examines acute myeloid leukemia with the 8;21 translocation, noting variations in blast percentages and a case with trisomy 21. It highlights key findings on leukemia biology and chromosome research.

    Area of Science:

    • Hematology
    • Cytogenetics
    • Oncology

    Background:

    • Acute myeloid leukemia (AML) is a heterogeneous cancer.
    • The 8;21 translocation is a recurring chromosomal abnormality in AML.
    • Accurate diagnosis relies on blast percentage and cytogenetic analysis.

    Observation:

    • Two AML cases with the 8;21 translocation presented with atypical blast counts.
    • One case uniquely featured the 8;21 translocation alongside constitutional trisomy 21.
    • The study incorporates findings from the 4th International Workshop on Chromosomes in Leukemia.

    Findings:

    • The 8;21 translocation can occur in AML cases not meeting standard blast count criteria.
    • Co-occurrence of 8;21 translocation and trisomy 21 presents a unique cytogenetic profile.

    Related Experiment Videos

  • New biological insights into AML associated with the 8;21 translocation were observed.

    • Implications:

    • Refines diagnostic criteria for AML with the 8;21 translocation.
    • Suggests further investigation into the role of trisomy 21 in AML pathogenesis.
    • Contributes to understanding the complex biology of acute myeloid leukemias.