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Perspectives in Pediatric Pathology, Chapter 22. Testicular Involvement in Systemic Diseases
Manuel Nistal1, Ricardo Paniagua2, Pilar González-Peramato1
11 Department of Pathology, Hospital La Paz, Universidad Autónoma de Madrid, Madrid 28029, Spain.
Abstract:
Normal testicular physiology requires appropriate function of endocrine glands and other tissues. Testicular lesions have been described in disorders involving the hypothalamus-hypophysis, thyroid glands, adrenal glands, pancreas, liver, kidney, and gastrointestinal tract. Testicular abnormalities can also associate with chronic anemia, obesity, and neoplasia. Although many of the disorders that affect the above-mentioned glands and tissues are congenital, acquired lesions may result in hypogonadism in children and adolescents.
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