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Related Concept Videos

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Related Experiment Video

Updated: Apr 21, 2026

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
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Anesthesia-free procedures for benign prostate obstruction: worth it?

Jan Ebbing1, Alexander Bachmann

  • 1Department of Urology, University Hospital Basel, Basel, Switzerland.

Current Opinion in Urology
|October 24, 2014
PubMed
Summary

Minimally invasive procedures offer alternatives for benign prostate obstruction when drug therapy fails. While promising, these treatments require local anesthesia and lack long-term data.

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Area of Science:

  • Urology
  • Minimally Invasive Surgery

Background:

  • Benign prostate obstruction affects many patients, with 30% not responding to drug therapy.
  • Traditional surgical interventions may pose risks for elderly or frail patients due to general anesthesia requirements.

Purpose of the Study:

  • To review recent advancements in minimally invasive procedures for benign prostate obstruction.
  • To evaluate alternatives to traditional surgery, focusing on those suitable for local anesthesia.

Main Methods:

  • Review of recent literature on mechanical devices and intraprostatic injections for benign prostate obstruction.
  • Analysis of data from randomized multicenter trials and early-phase studies.

Main Results:

  • The UroLift system shows promise in short-term trials.
  • Intraprostatic injections (NX1207, PRX302) have interesting early-phase results.
  • Rezum steam therapy and transurethral microwave therapy require further evaluation.

Conclusions:

  • Minimally invasive procedures for benign prostate obstruction generally require local anesthesia, with some needing sedation.
  • Pain management protocols are often not well-described in current studies.
  • While short-term outcomes are encouraging, long-term efficacy data is still lacking.