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Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
Published on: May 20, 2014
Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian small cell cancers
Nicholas Simon Reed1, Patricia Pautier, Elizabeth Åvall-Lundqvist
1*Beatson Oncology Centre, Glasgow, UK; †Institut Gustave Roussy, Villejuif, France; ‡Karolinska Intitute, Stockholm, Sweden; §Samsung Medical Centre, Sung Kyun Kwan University Medical Centre, Seoul, South Korea; ¶University of Duisberg, Essen, Germany; ∥National Health and Medical Research Council, Clinical Trials Centre, New South Wales, Australia; #Princess Margaret Hospital, Toronto, Canada; **Flinders Centre for Innovation in Cancer, South Australia, Australia; ††Centre hospitalier de l'Universite de Montreal, Montreal, Canada; and ‡‡Centre Leon Berard, Lyon, France.
Abstract:
Small cell carcinomas of the ovary are uncommon and account for less than 1% of ovarian cancers. They were first recognized in 1979, and a number of reports appeared during the next 2 decades. They are highly aggressive tumors and usually carry a poor prognosis, although this may reflect that most are diagnosed at advanced stage; however, those diagnosed as stage 1A have only 30% to 40% of long-term survivors. More reports followed extending our experience in the diagnosis and management of these rare cancers. The classification is described below and shown in Table 1, but a revision is expected to be published from the World Health Organization in 2014.

