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Metabolic changes in the liver of mice with Ehrlich ascites carcinoma
E V Inzhevatkin1, A A Savchenko
1Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia, inscience@mail.ru.
Bulletin of Experimental Biology and Medicine
|October 25, 2014
Abstract:
The dynamics of NADP-dependent dehydrogenase activity and malonic dialdehyde content in the liver were studied in mice with Ehrlich ascites carcinoma. Tumor growth was accompanied by the development of conditions for an increase in the intensity of energy metabolism and amphibolic role of the tricarboxylic acid cycle in LPO activation in liver cells.
