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Updated: Apr 21, 2026

Generation and Culturing of Primary Human Keratinocytes from Adult Skin
Published on: December 22, 2017
[Hereditary palmoplantar keratoderma - a focus on clinical and molecular genetic aspects]
Shailajah Kamaleswaran1, Lilian Bomme Ousager, Rasmus Overgaard Bach
1Klinisk Genetisk Afdeling, Aalborg Universitetshospital, Ladegårdsgade 5, 9000 Aalborg. shailajah@hotmail.com.
Abstract:
Hereditary palmoplantar keratoderma comprises a heterogenous group of genodermatoses. The clinical spectrum of palmoplantar keratoderma can range from pure skin thickening, restricted to palmoplantar skin to complex conditions with dental anomalies, eye symptoms, deafness, cardiac disease and cancer. The classification of hereditary palmoplantar keratoderma has been complicated. In recent years the molecular genetic background has been clarified for an increasing number of palmoplantar keratodermas, which makes it possible to make a more accurate diagnosis.
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