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Updated: Apr 21, 2026

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling
Published on: February 5, 2019
[Pharmaceutical treatment of lactation deficiency lacks evidence]
Paul Bryde Axelsson1, Flemming Bjerrum, Ellen Christine Leth Løkkegaard
1Gynækologisk-obstetrisk Afdeling, Nordsjællands Hospital, Dyrehavevej 29, 3400 Hillerød. paulbryde@gmail.com.
Abstract:
In this review we have looked at the evidence for the pharmacological treatment of lactation deficiency. Five RCTs (n = 166) of metoclopramide found no effect on lactation and two RCTs (n = 26) of older date and lesser quality found significant effect. One RCT (n = 51) of syntocinon found no effect on lactation and two older RCTs (n = 60) of lesser quality found significant effect. Three RCTs (n = 105) found significant effect of domperidone on lactation. Education on breastfeeding is important to avoid the need for pharmacological treatment.
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