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Functional-structural correlations in the afferent visual pathway in pediatric demyelination.

E Ann Yeh1, Ruth Ann Marrie2, Y Arun Reginald2

  • 1From the Divisions of Neurology (E.A.Y., A.E.N., J.O.) and Ophthalmology (Y.A.R., J.R.B.) and Department of Pediatrics (E.A.Y., A.E.N., J.O.), Hospital for Sick Children, University of Toronto; the Departments of Internal Medicine and Community Health Sciences (R.A.M.), University of Manitoba, Winnipeg, Canada; the Division of Neurology (B.B.), Children's Hospital of Philadelphia, University of Pennsylvania; and Department of Pediatrics (J.K.M.), the University of Calgary (F.C.), Canada. ann.yeh@sickkids.ca.

Neurology
|November 2, 2014
PubMed
Summary

Children with demyelinating disorders show reduced retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness. This retinal thinning correlates with decreased visual acuity and visual field sensitivity, suggesting primary neuronal injury.

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