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Antimicrobial activity of preparation Bioaron C
Acta Poloniae Pharmaceutica
|November 4, 2014
Summary
Sirupus Bioaron C, derived from Aloe arborescens, demonstrates potent antimicrobial activity against common respiratory pathogens. This natural preparation shows promise as a complementary treatment for upper respiratory tract infections, particularly in children.
Area of Science:
- Pharmacology
- Microbiology
- Natural Product Chemistry
Background:
- Upper respiratory tract infections (URTIs) are frequently caused by a variety of bacterial and fungal pathogens.
- Antimicrobial resistance necessitates the exploration of alternative therapeutic agents.
- Aloe arborescens extracts have demonstrated various biological activities, including potential antimicrobial effects.
Purpose of the Study:
- To evaluate the in vitro antimicrobial activity of sirupus Bioaron C, a preparation containing Aloe arborescens extract.
- To determine the efficacy of Bioaron C against key pathogens responsible for URTIs.
- To assess Bioaron C as a potential adjunct or alternative therapy for respiratory infections.
Main Methods:
- Antimicrobial activity testing of sirupus Bioaron C against 40 clinical isolates (anaerobic bacteria, aerobic bacteria, Candida species) and 18 reference strains (ATCC).
- Determination of Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) at undiluted concentration.
- Minimum Inhibitory Concentration (MIC) was compared to typically applied concentrations.
Main Results:
- Bioaron C exhibited significant biocidal activity (MBC/MFC) against prevalent URTIs pathogens, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Pseudomonas aeruginosa, and Candida albicans.
- Effective antimicrobial action was observed within 15 minutes at the producer-recommended concentration.
- The MIC values for Bioaron C were notably lower (5-100 times) than commonly used concentrations for most tested microorganisms.
Conclusions:
- Sirupus Bioaron C possesses strong antimicrobial properties against a broad spectrum of respiratory pathogens.
- The preparation demonstrates potential for use in the prevention and treatment of upper respiratory tract infections.
- Bioaron C may serve as a valuable alternative or complementary option to conventional therapies, especially for pediatric patients.
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