Right ventricle inflow obstructing mass proven to be a synovial sarcoma

Area of Science:

• Cardiology
• Oncology
• Pathology

Background:

• Soft tissue sarcoma is the most frequent malignant cardiac tumor.
• Common presentations include embolization, obstruction, and arrhythmogenesis.
• Cardiac tumors are rare, with sarcomas being the most common malignancy.

Observation:

• A 27-year-old male presented with nausea and dyspnea on exertion.
• Imaging revealed a large right heart mass extending into the inferior vena cava and right renal vein, reaching the kidney.

Findings:

• The cardiac mass was surgically resected.
• Immunohistochemical analysis confirmed the tumor as a TLE1-positive synovial sarcoma.

Implications:

• This case highlights an unusual presentation of cardiac synovial sarcoma with extensive venous and renal involvement.
• Early diagnosis and surgical management are crucial for managing cardiac sarcomas.
• Adjuvant chemotherapy may be considered in the treatment of cardiac synovial sarcoma.