Does interferon beta-1a impact pure-tone hearing sensitivity among individuals with multiple sclerosis?

M Samantha Lewis1, Garnett P McMillan, Michele Hutter

  • 1Garnett P. McMillan, PhD, is a Biostatistician at NCRAR, Portland VA Medical Center, Portland, OR. Michele Hutter, MS, was a Research Audiologist at the NCRAR, Portland VA Medical Center, Portland, OR. Robert L. Folmer, PhD, is a Research Investigator at NCRAR, Portland VA Medical Center, and Associate Professor, Department of Otolaryngology/Head and Neck Surgery, Oregon Health & Science University, Portland, OR. Debra Wilmington, PhD, was a Research Investigator at NCRAR, Portland VA Medical Center, Portland, OR and an Assistant Professor, Department of Otolaryngology/Head and Neck Surgery, Oregon Health & Science University, Portland, OR; and is currently an Instructor, Department of Biology, College of Arts and Sciences, Washington State University Vancouver, Vancouver, WA. Linda Casiana, MS, CCRP, was a Research Assistant at NCRAR, Portland VA Medical Center, Portland, OR. Mary Fitzpatrick, NP, was a Nurse Practitioner in the Neurology Service, Portland VA Medical Center; and is currently Medical Science Clinical Liaison, Biogen Idec U.S. Medical, Cambridge, MA. David J. Lilly, PhD, was a Research Investigator/Audiologist at NCRAR, Portland VA Medical Center, Portland, OR and is a Professor Emeritus, Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA. Dennis Bourdette, MD, is Co-Director, Multiple Sclerosis Center of Excellence West, Portland VA Medical Center, Portland, OR and Chair and Roy and Eulalia Swank Family Research Professor, Department of Neurology, Oregon Health & Science University, Portland, OR. Shannon Overs, MD, is a Staff Physician previously associated with the Neurology Service, Portland VA Medical Center, Portland, OR; Department of Neurology, Oregon Health & Science University, Portland, OR; and Novant Health Neurology Specialists, Charlotte, NC. Michelle Cameron, MD, is Staff Neurologist, Neurology Service, Portland VA Medical Center, and Assistant Professor, Department of Neurology, Oregon Health & Scienc

Summary

This study found insufficient evidence that interferon beta-1a causes hearing loss in multiple sclerosis patients, except possibly at 8000 Hz. Further research and hearing monitoring are recommended for patients on this treatment.