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Management of refractory Leber miliary aneurysms with macular edema: a case report
Sambath Tiroumal1, Andrew Lotery
1*Southampton Eye Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom; and †Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Purpose:
To report a case study of a patient with Leber miliary aneurysms with macular edema refractory to various treatment modalities.
Methods:
This is a retrospective study of a 35-year-old man who had multiple Leber miliary aneurysms with exudation and edema involving the macula. The patient's data were collected from case notes over a 3-year period of management of the condition.
Results:
The patient's Leber miliary aneurysm with exudation and macular edema was refractory to various treatment modalities, including laser photocoagulation, anti-vascular endothelial growth factor injections, photodynamic therapy, and cryotherapy. However, recently, the patient showed a good response to treatment with intravitreal dexamethasone implants. His macular edema and vision have improved with these injections.
Conclusion:
Intravitreal dexamethasone implants should be considered along with other treatment options when planning treatment of Leber miliary aneurysms. However, the long-term stability of the disease with these injections is not known.
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