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Updated: Apr 21, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Macular pits and scleral dehiscence in highly myopic eyes with macular chorioretinal atrophy
Kyoko Ohno-Matsui1, Masahiro Akiba, Muka Moriyama
1*Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Tokyo, Japan; and †Topcon Corporation, Tokyo, Japan.
Background:
In highly myopic eyes, it is possible to observe the entire thickness of the sclera using swept-source optical coherence tomography. The peculiar scleral alterations observed using swept-source optical coherence tomography within the area of macular chorioretinal atrophy were reported.
Methods:
The area of macular chorioretinal atrophy was scanned by swept-source optical coherence tomography in two patients with pathologic myopia.
Results:
In one of the two patients, three pitlike clefts were observed within the area of the atrophy. The deepest pit was 715 μm in depth from its opening. In the other patient, the sclera seemed to dehisce within the area of macular atrophy. In the adjacent sections of the scleral dehiscence, choroidal thickening was observed.
Conclusion:
These suggest that in the area of macular chorioretinal atrophy, the scleral curvature could be severely altered. The area of chorioretinal atrophy could expand more than the surrounding area due to a lack of RPE, Bruch membrane, and choriocapillaris.
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