Related Experiment Video
Updated: Apr 21, 2026
05:14
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
1.7K
Familial bilateral macular aneurysmal telangiectasia
Hideki Koizumi1, Bryan K Rutledge, Lawrence A Yannuzzi
1From *The LuEsther T. Mertz Retina Research Center of Manhattan Eye, Ear, and Throat Hospital, New York, and Vitreous-Retina-Macula Consultants of New York, New York; and †The Retina Vitreous Surgeons of Central New York, P.C., New York, New York.
Retinal Cases & Brief Reports
|November 13, 2014
Summary
This study reports the first known case of familial bilateral Coats
Area of Science:
- Ophthalmology
- Medical Genetics
Background:
- Idiopathic macular aneurysmal telangiectasia, or Coats' disease, is typically unilateral and affects males.
- Bilateral occurrence and familial cases are exceptionally rare.
Purpose of the Study:
- To report a rare familial occurrence of bilateral Coats' disease.
- Document a father-daughter case of this condition.
Main Methods:
- Clinical examination of affected individuals.
- Diagnostic confirmation using fluorescein angiography.
- Imaging with optical coherence tomography.
Main Results:
- A father and daughter presented with bilateral macular angiopathy.
- Findings included telangiectasia, aneurysms, ischemia, leakage, and lipid deposition.
- No associated systemic diseases were identified.
Conclusions:
- This is the first reported instance of familial bilateral Coats' disease in a father and daughter.
- The condition occurred without any associated systemic abnormalities in this family.
