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Acute macular neuroretinopathy: an atypical case

Maziar Lalezary1, Scott D Schoenberger, Edward Cherney

  • 1Vanderbilt Eye Institute and Vanderbilt School of Medicine, Nashville, Tennessee.

Retinal Cases & Brief Reports
|November 13, 2014
PubMed
Abstract

Insights

This case report details atypical acute macular neuroretinopathy (AMNR) lesions. Factors like flu-like illness and medication overdose may compound AMNR, affecting the outer plexiform layer.

Area of Science:

  • Ophthalmology
  • Retinal Diseases

Background:

  • Acute macular neuroretinopathy (AMNR) is a rare condition affecting the macula.
  • Understanding its diverse clinical presentations and contributing factors is crucial.

Purpose of the Study:

  • To describe extensive acute macular neuroretinopathy lesions with atypical features.
  • To highlight potential compounding factors in AMNR development.

Main Methods:

  • Retrospective case report.
  • Analysis of fundus imaging (autofluorescence, infrared), fluorescein angiography, and optical coherence tomography (OCT).

Main Results:

  • A patient presented with AMNR associated with flu-like illness, sympathomimetic exposure, overdose of norepinephrine reuptake inhibitors, anemia, thrombocytopenia, and hypotensive shock.
  • Fundus lesions mimicked retinal hemorrhages; OCT revealed outer plexiform layer opacification and photoreceptor abnormalities.

Conclusions:

  • Suggests a compounding effect of multiple factors in AMNR.
  • Outer plexiform layer abnormalities may correlate with the condition's temporal course.

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