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Parafoveolar intraretinal crystals in pearson syndrome
Sri Maguluri1, Franco M Recchia
1From Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee.
Retinal Cases & Brief Reports
|November 13, 2014
Summary
Bilateral parafoveolar intraretinal crystals were observed in a patient with Pearson syndrome (bone marrow-pancreas syndrome). These macular crystals may not significantly impact vision and suggest Pearson syndrome in differential diagnoses.
Area of Science:
- Ophthalmology
- Genetics
- Pediatrics
Background:
- Pearson syndrome is a rare multisystem disorder.
- Ocular manifestations of Pearson syndrome are not well-documented.
Purpose of the Study:
- To report the presence of bilateral parafoveolar intraretinal crystals in a patient diagnosed with Pearson syndrome.
- To highlight a potential ocular finding in Pearson syndrome.
Main Methods:
- A comprehensive ophthalmic examination was performed.
- Optical coherence tomography (OCT) was utilized for detailed imaging.
Main Results:
- Bilateral, fine, refractile, crystalline deposits were identified in the parafoveolar intraretinal space.
- No signs of pigmentary retinopathy or ophthalmoplegia were observed.
Conclusions:
- Intraretinal macular crystals can occur in Pearson syndrome.
- These crystalline deposits may not lead to significant visual acuity reduction.
- Pearson syndrome should be considered in the differential diagnosis of parafoveolar crystalline retinopathy.
