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Updated: Apr 16, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Amyloidogenic pituitary prolactinoma
Bakialakshmi Velayutham1, Mukund N Sable1, S Arunkumar2
1Department of Pathology and Lab Medicine, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
Abstract:
A 29-year-old man presented with a headache and right-sided visual deficit. His neurological examination was normal except for bilateral optic atrophy. CEMRI revealed a uniformly contrast-enhancing multilobulated lesion at the sellar and suprasellar region. Prolactin levels were high, with the value of 12,800 ng/mL (normal range 3-5 ng/mL) according to hormonal analysis. The pituitary adenoma was removed transsphenoidally from the patient. Histological examination revealed an adenoma with spheroid amyloid deposits adjacent to prolactin-staining adenoma cells. The patient recovered from the surgery without any complications.
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