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Updated: Apr 21, 2026
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Optical coherence tomography features of x-linked choroideremia
Aude Affortit-Demoge1, Giuseppe Querques, Cecilia Angulo-Bocco
1From the *Department of Ophthalmology, University of Paris XII, Centre Hospitalier Intercommunal de Creteil, Creteil, France; and the †Department of Ophthalmology, Ospedali Riuniti, University of Foggia, Foggia, Italy.
Purpose:
To describe the optical coherence tomography (OCT) features of X-linked choroideremia (CHM).
Design:
Prospective, observational case series.
Patients And Methods:
Color fundus photography, fluorescein angiography, indocyanine green angiography, and OCT were performed for four patients (eight eyes) with CHM.
Results:
In areas of angiographic choriocapillaris loss, OCT revealed retinal thinning (mean, 124 μm [range, 97-150 μm) and increased reflectivity of the choroid. On the contrary, in areas of preserved choriocapillaris, retinal thickness was within normal limits (mean, 256 μm [range, 238-284 μm]; P < 0.001).
Conclusion:
OCT revealed a correlation between retinal thickness and choriocapillaris preservation in CHM.
