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Updated: Apr 21, 2026

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle
Published on: January 30, 2019
Assessment of a Cambridge Structural Database-driven overlay program
Ilenia Giangreco1, Tjelvar S G Olsson, Jason C Cole
1Cambridge Crystallographic Data Centre , 12 Union Road, Cambridge CB2 1EZ, United Kingdom.
Abstract:
We recently published an improved methodology for overlaying multiple flexible ligands and an extensive data set for validating pharmacophore programs. Here, we combine these two developments and present evidence of the effectiveness of the new overlay methodology at predicting correct superimpositions for systems with varying levels of complexity. The overlay program was able to generate correct predictions for 95%, 73%, and 39% of systems classified as easy, moderate, and hard, respectively.
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