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The 'Sphere': A Dedicated Bifurcation Aneurysm Flow-Diverter Device
Thomas Peach1, J Frederick Cornhill2, Anh Nguyen2
1Institute of Biomedical Engineering, Department of Engineering Science, Oxford University, Oxford, UK.
Cardiovascular Engineering and Technology
|November 18, 2014
Summary
The novel
Area of Science:
- Biomedical Engineering
- Medical Devices
- Computational Fluid Dynamics
Background:
- Bifurcation aneurysms in the cerebral vasculature pose significant treatment challenges.
- Current flow-diverter devices have limitations in treating complex aneurysm geometries.
Purpose of the Study:
- To evaluate the early-stage design of the 'Sphere' flow-diverter prototype for treating bifurcation aneurysms.
- To assess the hemodynamic effects of the 'Sphere' device using computational modeling.
Main Methods:
- Computational modeling and simulation of the 'Sphere' device in six anatomically accurate cerebral bifurcation aneurysms.
- Utilizing both steady state and transient flow simulations to analyze device performance.
- Assessing aneurysm inflow reduction and wall shear stress (WSS) changes.
Main Results:
- The 'Sphere' device demonstrated significant aneurysm inflow reduction, ranging from 30.6% to 71.8%.
- The device effectively reduced WSS magnitude within the aneurysm sac, promoting a healthier hemodynamic environment.
- A notable difference was observed between steady state and transient simulations in capturing flow recirculation.
Conclusions:
- The 'Sphere' flow-diverter shows promise for treating bifurcation aneurysms with substantial flow reduction and improved hemodynamics.
- The device offers potential advantages over existing cylindrical flow-diverter designs.
- Further analysis of mechanical properties and deployability is warranted.
