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Development of an EORTC-8D utility algorithm for Sri Lanka.

Sanjeewa Kularatna1, Jennifer A Whitty2, Newell W Johnson3

  • 1Centre for Applied Health Economics, School of Medicine, Griffith University, Queensland, Australia (SK, PAS)

Medical Decision Making : an International Journal of the Society for Medical Decision Making
|November 19, 2014
PubMed
Summary
This summary is machine-generated.

Researchers developed a new way to value cancer patient health in Sri Lanka. This utility algorithm for the EORTC-8D measure will aid economic evaluations in low- and middle-income countries.

Keywords:
EORTC-8DQALYSri LankaTTOhealth state valuationutility

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Area of Science:

  • Health Economics
  • Oncology
  • Psychometrics

Background:

  • Cancer-specific health state valuations are lacking in low- and middle-income countries.
  • The European Organisation for Research and Treatment of Cancer (EORTC-8D) is a validated preference-based measure with 81,920 health states for economic evaluations in cancer care.

Purpose of the Study:

  • To develop a utility algorithm for valuing EORTC-8D health states.
  • To derive preferences from a representative population sample in Sri Lanka.

Main Methods:

  • Utilized the time-tradeoff method with a general population sample (n=780) in Sri Lanka.
  • Employed a block design of 85 health states with a 10-year time horizon for direct valuation.
  • Analyzed data using generalized least squares with random effects, excluding logically inconsistent responses.

Main Results:

  • Analysis included 4520 observations from 717 respondents after exclusions.
  • The preferred model incorporated main effects and an interaction term for health state descriptors.
  • Deterioration in physical functioning resulted in a significant utility decrement in this population.

Conclusions:

  • Preference weights for EORTC-8D health states in Sri Lanka have been successfully derived.
  • These derived weights are valuable for economic evaluations of cancer interventions in low- and middle-income countries.