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[Preventive effect of behavioral therapy plus flunarizine in children with migraine]

Yan-Zhao Chen1, Ning Li, Ke-Ying Zhou

  • 1Department of Pediatrics, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen, Guangdong 518020, China. zhoukeying@163.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|November 20, 2014
PubMed

Insights

Behavioral therapy combined with flunarizine effectively reduced migraine symptoms in children. This combination therapy showed superior clinical efficacy compared to flunarizine alone for pediatric migraine prevention.

Area of Science:

  • Pediatric neurology
  • Clinical pharmacology

Context:

  • Migraine is a common neurological disorder in children, significantly impacting their quality of life.
  • Current treatment strategies for pediatric migraine often involve pharmacological and non-pharmacological approaches.

Purpose:

  • To evaluate the preventive efficacy of behavioral therapy combined with flunarizine in pediatric migraine patients.
  • To compare the effectiveness of combination therapy versus flunarizine monotherapy.

Summary:

  • A randomized controlled trial involving 90 pediatric migraine patients compared behavioral therapy plus flunarizine against flunarizine alone over 3 months.
  • The combination therapy group showed statistically significant improvements in the Pediatric Migraine Disability Assessment Score (PedMIDAS) and Bussone headache index compared to the control group.

Impact:

  • Behavioral therapy plus flunarizine demonstrates enhanced clinical efficacy for preventing migraine in children.
  • This combined therapeutic approach offers a promising strategy for managing pediatric migraine.
  • Findings support the integration of behavioral interventions into pharmacological treatment plans for children with migraine.
Abstract

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