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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Robotic Enucleation of Esophageal Leiomyoma
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Robotic Enucleation of Esophageal Leiomyoma

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Cutaneous leiomyosarcoma - Case report.

M E Ciurea1, C V Georgescu2, C C Radu3

  • 1Department of Plastic and Reconstructive Surgery, Craiova University of Medicine and Pharmacy.

Journal of Medicine and Life
|November 20, 2014
PubMed
Summary
This summary is machine-generated.

Cutaneous leiomyosarcoma (CLM) is a rare skin cancer. Early surgical excision is key, but prognosis remains poor due to high recurrence rates, necessitating long-term patient monitoring.

Keywords:
leiomyosarcomapleomorphicskin

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Cutaneous leiomyosarcoma (CLM) is an exceptionally rare malignancy originating from smooth muscle tissue within the skin.
  • Superficial leiomyosarcomas constitute approximately 3% of all soft tissue sarcomas.

Observation:

  • CLM typically manifests as a firm, solitary dermal nodule, ranging from 1-3 cm in diameter.
  • Symptoms can include pain, itching, or paresthesia, and lesions may appear on the face, trunk, or chest.
  • This rare tumor affects individuals of all ages, with a notable peak incidence in the 60-70 year age group.

Findings:

  • Diagnosis of CLM can be challenging due to its nonspecific clinical presentation.
  • Surgical excision with wide oncological margins is the primary treatment modality.
  • Radiotherapy and chemotherapy have demonstrated limited efficacy in managing CLM.

Implications:

  • Despite aggressive surgical intervention, CLM exhibits significant recurrence rates, contributing to a generally poor prognosis.
  • Long-term follow-up is crucial for detecting potential disease progression or new malignant conditions.
  • Further research into effective therapeutic strategies and prognostic factors for CLM is warranted.