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Dermoscopy Patterns and Histopathological Findings in Nodular Basal Cell Carcinoma-Study on 68 Cases.
A O Enache1, V Pătrașcu1, C E Simionescu2
1Department of Dermatology, University of Medicine and Pharmacy of Craiova, Romania.
Current Health Sciences Journal
|July 13, 2019
Summary
Basal cell carcinoma (BCC), the most common skin cancer, shows increasing incidence in young Europeans. Irregular vascularity and translucency are key dermoscopic features of nodular BCC, aiding diagnosis.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Basal cell carcinoma (BCC) is the most prevalent form of skin cancer, with rising incidence rates, particularly among younger populations in Europe.
- Nodular basal cell carcinoma represents the most common histological subtype, accounting for a significant majority of BCC cases.
Observation:
- An observational morphological study included 68 patients diagnosed with nodular BCC.
- Data collected encompassed lesion localization, diameter, histological subtype, dermoscopic patterns, Fitzpatrick skin type, and patient sex.
- The most frequent dermoscopic pattern observed was irregular vascularity, with arborizing vessels being the predominant irregular vascular pattern.
Findings:
- Irregular vascularity and arborizing vessels were the most common dermoscopic features in nodular BCC.
- Translucency was identified as the second most frequent dermoscopic feature.
- In pigmented BCCs, common features included pigmented islands, specific pigmented distribution patterns, arborizing vessels, and white streaks/areas.
- Histopathological analysis confirmed nodular BCC in 71.7% of the studied cases.
Implications:
- Dermoscopic patterns like irregular vascularity and translucency are crucial for identifying nodular basal cell carcinoma.
- Accurate differential diagnosis of basal cell carcinoma is essential to prevent severe morbidity associated with delayed or missed diagnoses.
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