Clear Cell Acanthoma with Atypical Location -Case Report and Literature Review

Area of Science:

• Dermatology
• Histopathology

Background:

• Clear cell acanthoma is an uncommon benign skin neoplasm.
• Typically affects middle-aged and elderly individuals, presenting as a solitary erythematous papule on the lower limbs.

Observation:

• An 80-year-old female presented with a 7-8 year history of a slow-growing, infiltrative, erythematous-squamous-crusty plaque in the right groin.
• The lesion measured 1.2/1.5 cm with a polycyclic shape.

Findings:

• Histopathological examination confirmed the diagnosis of clear cell acanthoma.
• The case is considered atypical due to the unusual location of the lesion.

Implications:

• Clear cell acanthoma diagnosis can be challenging due to its varied presentation and differential diagnoses.
• Histopathological examination is crucial for definitive diagnosis.
• Treatment typically involves surgical excision.