Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colors and Magnetism03:02

Colors and Magnetism

14.9K
Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
14.9K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

32.3K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
32.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of Line Width and Anisotropy in <i>C</i><sub>3</sub>/<i>C</i><sub>4</sub>-Symmetric Gd(III) Complexes.

Inorganic chemistry·2026
Same author

Volume and Tempo: Cortical Excitability and Trial-to-Trial Consistency of Auditory Responses Distinguish Psychosis Biotypes.

Research square·2026
Same author

Protein binding regulates complex configuration: comparative analysis of three dynamically racemic europium(iii) complexes.

RSC advances·2026
Same author

Absolute Temperature Mapping Using Chiral Terbium Parashift Complexes for MRI Thermometry.

Chemical & biomedical imaging·2026
Same author

Silicone vs. Silicon/Silica in Intraoral Healing: A Systematic Review.

Materials (Basel, Switzerland)·2026
Same author

Synthesis and preliminary assessment of fluorescent probes based on the competitive GPCR antagonists vismodegib and masupirdine.

RSC advances·2026

Related Experiment Video

Updated: Apr 20, 2026

An Aptamer-based Sensor for Unchelated GadoliniumIII
05:15

An Aptamer-based Sensor for Unchelated GadoliniumIII

Published on: January 9, 2017

7.9K

Optimizing the high-field relaxivity by self-assembling of macrocyclic Gd(III) complexes.

Dale Lawson1, Alessandro Barge, Enzo Terreno

  • 1Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza, 52, 10126, Torino, Italy.

Dalton Transactions (Cambridge, England : 2003)
|November 21, 2014
PubMed
Summary

New dimeric gadolinium(III) compounds show enhanced relaxivity. This is achieved by optimizing hydration spheres using specific recognition moieties for improved magnetic resonance imaging contrast agents.

More Related Videos

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

15.5K
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

10.7K

Related Experiment Videos

Last Updated: Apr 20, 2026

An Aptamer-based Sensor for Unchelated GadoliniumIII
05:15

An Aptamer-based Sensor for Unchelated GadoliniumIII

Published on: January 9, 2017

7.9K
Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

15.5K
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
11:27

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

10.7K

Area of Science:

  • Inorganic Chemistry
  • Materials Science
  • Radiochemistry

Background:

  • Gadolinium(III) complexes are widely used as contrast agents in magnetic resonance imaging (MRI).
  • Relaxivity, a measure of contrast agent efficiency, is influenced by water molecule dynamics in the inner and second coordination spheres.
  • DO3A-type complexes offer a versatile platform for developing novel MRI contrast agents.

Purpose of the Study:

  • To synthesize novel dimeric poly(aminocarboxylate) gadolinium(III) compounds.
  • To investigate the effect of recognition moieties on the relaxivity of these dimeric complexes.
  • To optimize the contributions of inner and second spheres of hydration for enhanced MRI contrast.

Main Methods:

  • Synthesis of dimeric poly(aminocarboxylate) gadolinium(III) compounds utilizing specific recognition moieties.
  • Characterization of the synthesized complexes.
  • Relaxivity measurements to evaluate their performance as MRI contrast agents.

Main Results:

  • Successful formation of dimeric gadolinium(III) compounds with enhanced relaxivities.
  • Demonstrated that recognition moieties binding to the inner coordination sphere optimize hydration sphere contributions.
  • Achieved significantly improved relaxivities compared to monomeric counterparts.

Conclusions:

  • Dimeric gadolinium(III) compounds with tailored recognition moieties offer a promising strategy for developing superior MRI contrast agents.
  • Optimization of inner and second sphere hydration is crucial for enhancing relaxivity.
  • These findings contribute to the advancement of molecular imaging technologies.