Related Experiment Video
Updated: Apr 20, 2026

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy
Published on: January 31, 2025
Ultrasound-Guided Regional Anesthesia for Pediatric Burn Reconstructive Surgery: A Prospective Study
Erik S Shank1, Jeevendra A Martyn, Mathias B Donelan
1From the *Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston; and †Department of Surgery, Shriners Hospital for Children®, Harvard Medical School, Boston.
Insights
Regional anesthesia, including lateral femoral cutaneous nerve (LFCN) blocks, significantly improved pain management for pediatric burn patients undergoing reconstructive surgery. These blocks offered better donor site comfort compared to local anesthetic infiltration.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Burn Reconstruction
Background:
- Pediatric burn patients often require multiple surgeries for reconstruction.
- Graft donor sites are frequently the most painful aspect, leading to procedure deferral.
- Effective pain management is crucial for pediatric reconstructive surgery outcomes.
Purpose of the Study:
- To compare the efficacy of local anesthetic infiltration versus regional nerve blocks for donor site analgesia in pediatric burn patients.
- To evaluate pain scores and comfort levels following different regional anesthesia techniques.
Main Methods:
- Nineteen pediatric patients were randomized into three groups: local anesthetic infiltration, single-shot ultrasound-guided LFCN block, or fascia iliaca compartment block with continuous catheter infusion.
- Postoperative pain was assessed using visual analog scale scores every 4 hours for 48 hours.
- Data was analyzed using nonparametric statistical tests (ANOVA, Friedman's, Kruskal-Wallis).
Main Results:
- Patients receiving regional anesthesia (LFCN or compartment block) reported significantly greater comfort than the local infiltration group.
- Single-shot LFCN block provided superior comfort on postoperative day 0.
- Continuous catheter infusion offered better comfort on postoperative days 1 and 2.
- No significant difference in opioid requirements was observed between groups.
Conclusions:
- Ultrasound-guided regional anesthetic blocks of the LFCN, with or without continuous catheter, enhance postoperative comfort for pediatric burn patients undergoing reconstructive surgery.
- Continuous catheter blocks may offer optimal comfort throughout the entire postoperative recovery period.
Abstract:
Pediatric patients face multiple reconstructive surgeries to reestablish function and aesthetics postburn injury. Often, the site of the harvested graft for these reconstructions is reported to be the most painful part of the procedure and a common reason for deferring these reconstructive procedures. This study in pediatric burn patients undergoing reconstructive procedures examined the analgesia response to local anesthetic infiltration versus either a single ultrasound-guided regional nerve block of the lateral femoral cutaneous nerve (LFCN) or a fascia iliaca compartment block with catheter placement and continuous infusion. Nineteen patients were randomized to one of three groups (infiltration, single-shot nerve block, or compartment block with catheter) and received intraoperative analgesia intervention. Postoperatively, visual analog scale pain scores were recorded-for pain at the donor site-every 4 hours while awake-for 48 hours. This nonparametric data was analyzed using a two-way ANOVA, Friedman's test, and Kruskal-Wallis test, with significance determined at P < 0.05. The analysis demonstrated that the patients in the regional anesthesia groups were significantly more comfortable over the 48 hour hospital course than the patients in the control group. The patients receiving a single-shot block of the LFCN were more comfortable on postoperative day (POD) 0 while the catheter patients were more comfortable on POD 1 and POD 2. There was not a statistically significant difference in opioid requirements in any group. Regional anesthetic block of the LFCN, with or without catheter placement, provides an improved postoperative experience for the pediatric patient undergoing reconstructive surgery with lateral/anterolateral skin graft versus local anesthesia infiltration of donor site. For optimal comfort throughout the postoperative period, an ultrasound-guided block with continuous catheter may be beneficial.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

