Related Experiment Video
Updated: Apr 20, 2026

08:22
Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
934
Pleural space complications associated with lung transplantation
Andrew Arndt1, Daniel J Boffa1
1Thoracic Surgery, Yale New Haven Hospital, New Heaven, CT 06510, USA.
Thoracic Surgery Clinics
|November 29, 2014
Summary
Lung transplantation is a vital treatment for end-stage lung disease. However, pleural space complications like hemothorax and empyema remain common challenges after surgery.
Area of Science:
- Thoracic Surgery
- Pulmonary Medicine
- Critical Care
Background:
- Lung transplantation offers a life-saving solution for patients with end-stage lung diseases.
- Surgical safety has improved, but perioperative morbidity remains a significant concern.
- Complications within the pleural space are frequently observed following lung transplant procedures.
Purpose of the Study:
- To review and discuss common pleural space complications after lung transplantation.
- To provide an overview of the management and clinical significance of these complications.
Main Methods:
- Literature review and synthesis of current knowledge on pleural complications post-lung transplant.
- Discussion of specific conditions including hemothorax, chylothorax, pneumothorax, and empyema.
Main Results:
- Pleural space complications are a common source of morbidity after lung transplantation.
- Identified complications include hemothorax, chylothorax, air leak (pneumothorax), recurrent effusion, empyema, trapped lung, and chronic pleural issues.
Conclusions:
- Despite advancements, managing pleural space complications remains critical for improving outcomes in lung transplant recipients.
- Awareness and prompt management of these complications are essential for patient recovery and long-term success.
Related Concept Videos
Pleura of the Lungs
11.4K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
11.4K
Pneumothorax II: Pathophysiology
21
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance...
21
Pneumothorax-I
2.1K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
2.1K
Pneumothorax-II
1.6K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
1.6K
Pleural Effusion I: Introduction
6.0K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
6.0K
Pleural Effusion II: Symptoms and Management
1.3K
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1.3K

